In this video we will discuss the formally published Final Report from the ACTT-1 group on Remdesivir to treat COVID-19. This was a therapy that President Trump received while hospitalized at Walter Reed. It is a viral RNA dependent RNA polymerase inhibitor that has proven efficacious in cell culture against SARS-CoV-2 virus. We will talk about this medication and how it works. The ACTT-1 trial was a larger randomized, double blinded, placebo control trial performed at 60 sites all over the world. What they found was that Remdesivir decreased duration of symptoms and trended towards a mortality improvement. We will dive into this trial. What do these conclusions mean? Is there more to the story? Check out the video for all the details on this medication that has been all over the news!

Link to study:

Remdesevir Videos:
ACTT-1 Trial in the New England Journal of Medicine Preceding Final Report:

COVID-19 and Remdesivir, Another Potential Therapy:

A compilation of Remdesevir COVID-19 videos:

First remdesevir video:

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There will be a running series of videos using the most up to date information on COVID-19, but this is an evolving field and new videos may come out that contradict that previous information. That is okay and is the nature of a fast paced and evolving clinical scenario. Stick with us as we work to unveil the intricacies of COVID-19, it’s clinical significance, and the societal implications. ***This is strictly educational and not to be mistaken as clinical recommendations, please verify all information with accepted guidelines and practice patterns.***

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THIS VIDEO DOES NOT PROVIDE MEDICAL ADVICE. The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read, watched, or listened to on this video, or any other videos, reports, texts tweets or other sources.

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  1. I discerned no bias. I have stopped giving it because there is a problem showing mortality benefit, just like the plasma trial. I feel Ivermectin would trend or better, but no studies done conclusively. I may reconsider those on oxygen alone, ( the bulk of hospital cases ), but in the era of dirt cheep steroid and MATH + therapy, that seems to be working, why add 1,600 dollars and 5 days IV to the bill? When randomized, controlled trials, of this and plasma, with thousands of patients are in, and not statistically significant, what are we debating about? These perks would NOT be extended to HCQ or Ivermectin, just sayin’!

  2. It appears that remdesivir is better than nothing in treating COVID-19. But its true benefit may be in helping to determine whether other factors, yet unknown (genetic, behavioral environmental, etc.), are influencing the progression of the disease.

  3. Was this study flawed from the start due to the fact that the median antiviral intervention started 9 days after symptoms? By symptomatic day 9, is the viral replication phase already starting to wind down?

    Any thoughts on better outcomes if the intervention started several days earlier when the virus is spending a great amount of its effort on replicating…say 5 or 6 days after symptom onset instead of 9?

  4. 😷😷😷World health Org: EXPOSED, Time line by 2 different doctors. The WHO needs to be held accountable, Dr.Campbell https://youtu.be/fxhZ2Z-Y4ls
    Reference books conflict with WHO Decisions Dr. Been: https://youtu.be/LOHtpFATzlI

    What is the WHO responsibility?
    https://youtu.be/AwFTZawOc9k

    Who is Director General Tedros? A politician not a medical Doctor? With very close ties to China. https://www.thegatewaypundit.com/2020/03/breaking-who-director-general-tedros-adhanom-ghebreyesus-was-reportedly-ranking-member-of-terrorist-organization-and-china-puppet/

    How China influenced the WHO "General Tedros"
    https://www.redstate.com/bonchie/2020/03/23/china-helped-get-who-director-general-elected-now-hes-returning-the-favor/

    Research, understand, education is important to our freedoms

    Why is Dr Fauci from the CDC not sharing with the public his emails with the WHO? https://youtu.be/WHYmHAIkjl4
    Coverup, stonewalling.
    Why is Dr. Fauci protecting the WHO?😷😷😷

  5. Thanks for checking out the video!

    @WhiteBoardDoct1

    http://www.patreon.com/WBDR

    https://www.buymeacoffee.com/WBDR

    Ivermectin Videos:

    IDEA Trial (Ivermectin, Dexamethasone, Enoxaparin, Aspirin) Mild, Mod, Sever COVID:

    https://www.youtube.com/watch?v=hX14ol0FYHg

    Ivermectin to Treat Hospitalized Patients with COVID-19:

    https://www.youtube.com/watch?v=_UvZHJh_wdk

    Ivermectin Inhibits RNA Dependent RNA Polymerase

    https://www.youtube.com/watch?v=1iRqTU1cp4E

    Ivermectin Post-Exposure Prophylaxis:

    https://www.youtube.com/watch?v=nJyyISQg85M

    Ivermectin and Doxycycline To Treat Mild to Moderate COVID-19:

    https://www.youtube.com/watch?v=2LjIMX_qwZ0

    Ivermectin, Hydroxychloroquine, and Azithromycin for Hospitalized COVID-19 patients:

    https://www.youtube.com/watch?v=UPWJ9uawqko

    Ivermectin and new mechanism; halting thrombi through inhibition of CD147:

    https://www.youtube.com/watch?v=l3yw1ggunfo

    ICON Trial:

    https://www.youtube.com/watch?v=ryWcke_-Fjs&t=388s

    In Vitro on Ivermectin for COVID-19, 99.99% Decrease in Viral Load:

    https://www.youtube.com/watch?v=npcuIWw6y1Q

    Ivermectin+Doxycyline Compared to Hydroxychloroquine+Azithromycin for COVID-19:

    https://www.youtube.com/watch?v=V2M-x5bUzjo

    HCQ +/- Azithromycin Videos:

    RECOVERY Trial HCQ for COVID-19:

    https://www.youtube.com/watch?v=viF14-W_1MM

    Low Dose HCQ to treat COVID-19:

    https://www.youtube.com/watch?v=ihEkCddeLOA

    HCQ, HCQ+Azithro, and Standard Care: RCT For COVID-19

    https://www.youtube.com/watch?v=ZKILEtUHC6Q

    HCQ Pre-Exposure Prophylaxis:

    https://www.youtube.com/watch?v=nIJDxEuu_Qw

    Outpatient use of HCQ for early COVID-19

    https://www.youtube.com/watch?v=V0_PkRkq3p4

    HCQ and Azithromycin 3,737 patient in France

    https://www.youtube.com/watch?v=My8PY97ZuAI&t=1040s

    Henry Ford Hospital Study decreased mortality with HCQ and HCQ+Azithro:

    https://www.youtube.com/watch?v=FSEtu5VUJQA

    French Data on 1,061 patients treated with HCQ +/- Azithro:

    https://www.youtube.com/watch?v=6E9bI1_-Xjs&t=102s

    Zinc Videos (+/- HCQ/azithro):

    HCQ (and Zn) Post-Exposure Prophylaxis:

    https://www.youtube.com/watch?v=UvbWQ9GyQ-4&t=1035s

    Zinc, Hydroxychloroquine, and Azithromycin for early COVID-19 in outpatients:

    https://www.youtube.com/watch?v=4eR0oV0Yqwo

    Triple Therapy Zinc, Hydroxychloroquine, and Azithromcyin:

    https://www.youtube.com/watch?v=EwS3BajTFDY&t=1347s

    COVID-19 and Zn, Another Potential Therapy!

    https://www.youtube.com/watch?v=Iuj4KYZXrGQ

    Remdesevir Videos:

    Final Report Remdesevir NEJM:

    https://www.youtube.com/watch?v=YgXAafDAbFk

    COVID-19 and Remdesivir, Another Potential Therapy:

    https://www.youtube.com/watch?v=qLXpGTY5sug&t=18s

    First Remdesevir video:

    https://www.youtube.com/watch?v=qLXpGTY5sug&t=180s

    Steroid Videos:

    Meta-analysis on Steroids in Sever COVID-19:

    https://www.youtube.com/watch?v=U1NVQD_7H1I

    Study on Early Steroid Use In COVID-19:

    https://www.youtube.com/watch?v=pge7xy-mVec

    The RECOVERY Trial on Dexamethasone in COVID-19:

    https://www.youtube.com/watch?v=pfu2Nt8WroI

    How does Dexamethasone work?

    https://www.youtube.com/watch?v=jrAj24eSR4o

    Other Anti-Virals:

    Carrageenan and Xylitol Inhibits SARS-CoV-2:

    https://www.youtube.com/watch?v=9t4xGa5hhC8

    EIDD – 2801: A Ribonucleoside Analog for COVID-19:

    https://www.youtube.com/watch?v=9YRh0M2TYyw

    Lopinavir/ritonavir for COVID-19:

    https://www.youtube.com/watch?v=sEKCfk8fVeE&t=407s

    Danoprevir to Treat COVID-19:

    https://www.youtube.com/watch?v=KRqhXxySYuk&t=75s

    Favipiravir for COVID-19, New Data:

    https://www.youtube.com/watch?v=D4hYJ9OgKyA&t=26s

    Study Comparing Favipiravir to Arbidol for COVID-19:

    https://www.youtube.com/watch?v=I-Ey1_7OR4A

    Study on Chloroquine, Remdesivir, Favipiravir, Ribavirin, Penciclovir, and Nafamostat: https://www.youtube.com/watch?v=EdRJ4BpHiNI&t=771s

    Inhaled Therapies:

    Inhaled IFNb (SNG001) for COVID-19

    https://www.youtube.com/watch?v=TKvbuWplCw8

    Inhaled nitric oxide for COVID-19:

    https://www.youtube.com/watch?v=y2zQkjZcfO4

    Inhaled Corticosteroids:

    https://www.youtube.com/watch?v=REZCbgvmPgA&t=1000s

    Vaccines:

    ChAdOx1 Vaccine Phases 1 and 2 Trial:

    https://www.youtube.com/watch?v=VwTuHm4yk9g

    Moderna mRNA-1273 Phase 1 Trial

    https://www.youtube.com/watch?v=CrPsat1Olas

    Other Therapies:

    Ceftazidime Inhibits Spike Protein Binding:

    https://www.youtube.com/watch?v=h-Wm_uOOWfY

    Vitamin D Supplementation to treat COVID-19:

    https://www.youtube.com/watch?v=QuvZCscApM4

    Icatibant Bradykinin Pathway COVID-19:

    https://www.youtube.com/watch?v=eWgV0K23PhM

    Aviptadil (RLF-100) Direct Inhibition Of SARS-CoV-2:

    https://www.youtube.com/watch?v=rq-8GlKF70k

    Aviptadil (RLF-100) Mechanism:

    https://www.youtube.com/watch?v=7OclhNydPDk

    Large Convalescent Plasma Study COVID-19:

    https://www.youtube.com/watch?v=Xlr7JreV3zI

    AVM0703 Novel Therapy COVID-19:

    https://www.youtube.com/watch?v=jnbUZgh5Jj4

    Aviptadil For COVID-19:

    https://www.youtube.com/watch?v=7OclhNydPDk

    Colchicine For COVID-19:

    https://www.youtube.com/watch?v=xGfD6BZFsNo

    Randomized Trial Bromhexine:

    https://www.youtube.com/watch?v=6NMy289l4II

    BCG vaccine and COVID-19

    https://www.youtube.com/watch?v=md1475QPPiY

    New Study on Pepcid/Famotidine Use For COVID-19:

    https://www.youtube.com/watch?v=NQkJKDUUctM

    New Study On Tocilizumab/Actemra:

    https://www.youtube.com/watch?v=65kjFG9t6X8&t=189s

    Lactoferrin as therapy for COVID-19

    https://www.youtube.com/watch?v=lwTUb2x0C4k&t=6s

    COVID-19 and immunoglobulin/convalescent plasma:

    https://www.youtube.com/watch?v=crD7tAUDW-o

    COVID-19 and NSAIDS:

    https://www.youtube.com/watch?v=37VVxsqCmRM

    COVID-19 and Camostat Mesylate:

    https://www.youtube.com/watch?v=mTBGWkOFN8o&t=75s

    Interferon to treat COVID-19:

    https://www.youtube.com/watch?v=C7CRurg7id4&t=1s

    COVID-19 Management Strategies Beyond The Treatments:

    Should you keep taking your statin with COVID-19?

    https://www.youtube.com/watch?v=yTDfYU5Wpd0

    ACEI/ARBs in COVID-19: Helpful, Hurtful, or Neither?

    https://www.youtube.com/watch?v=3IFqRLtQrIQ&t=151s

    Proning COVID-19:

    https://www.youtube.com/watch?v=rHW_bxXKAtI

    Splitting Ventilators:

    https://www.youtube.com/watch?v=0Lsv7mxbd1o&t=62s

    Organ Systems:

    COVID-19 Affecting the Heart:

    https://www.youtube.com/watch?v=2iRA7kGc_Pw&t=19s

    COVID-19, The Brain, and The Blood Brain Barrier:

    https://www.youtube.com/watch?v=30p7q082Qqw&t=72s

    https://www.youtube.com/watch?v=A4NLRjLCxo0

    COVID-19 and it’s effect on the kidneys:

    https://www.youtube.com/watch?v=capCRENmDMc&t=336s

    COVID-19 and the Lungs:

    https://www.youtube.com/watch?v=rrHn4SzUl1U&t=23s

    COVID-19 and Gastrointestinal Symptoms:

    https://www.youtube.com/watch?v=hGtWff0EOzg&t=2s

    https://www.youtube.com/watch?v=4UjSVEH51mk

    Pathophysiology of COVID-19:

    Bradykinin, ACE2, and Respiratory Failure in COVID-19:

    https://www.youtube.com/watch?v=92JklQjTluc

    COVID-19 Reinfection With Different Viral Strains:

    https://www.youtube.com/watch?v=wTpPZdHBpdk

    Memory T Cell Response to COVID-19:

    https://www.youtube.com/watch?v=IS9SspyZcK8

    Cross Immunity To COVID-19:

    https://www.youtube.com/watch?v=o1qZlZmuRQg

    Two different invasion techniques SARS-CoV-2 and how that affects therapies:

    https://www.youtube.com/watch?v=c6JuvEOjF1U

    COVID Toes or Chilblains:

    https://www.youtube.com/watch?v=DxaIgfmdKmA

    Waning immunity against SARS-CoV-2:

    https://www.youtube.com/watch?v=7B7-T_5a8Hk

    ABO Blood Types and Other Genetic Predispositions

    https://www.youtube.com/watch?v=gTXZz-H-t6w

    COVID-19 Strokes and Lupus Anticoagulant:

    https://www.youtube.com/watch?v=IPeJV-linbc&t=394s

    COVID-19 and Hypercoagulability:

    https://www.youtube.com/watch?v=L6Cyfzy3xiY&t=504s

    SARS-CoV-2 and human hemoglobin molecules, do they interact?

    https://www.youtube.com/watch?v=xm_up_2Vg7w&t=1s

    New Study Showing COVID-19 Mutating and Changing Pathogenicity:

    https://www.youtube.com/watch?v=CuKNFkGLQ7k

    Angiotensin II and COVID-19:

    https://www.youtube.com/watch?v=m7MnwJvfpxQ&t=201s

    COVID-19 and ARDS, The Syndrome That Is Killing People:

    https://www.youtube.com/watch?v=rrHn4SzUl1U&t=23s

    Understanding the Immune System Through COVID-19 and BCG:

    https://www.youtube.com/watch?v=R-sR5GXMi2Q&t=27s

    COVID-19 and smoking:

    https://www.youtube.com/watch?v=h3nKlldMHy0&t=1s

    Acute Necrotizing Encephalopathy and COVID-19:

    https://www.youtube.com/watch?v=2YfHG7Jyp8s&t=300s

    Pediatrics:

    Update on Multisystem Inflammatory Syndrome from 86 children across USA

    https://www.youtube.com/watch?v=iwzXH60tbDM

    The first large cohort of pediatric patients with COVID-19:

    https://www.youtube.com/watch?v=vwgUHtnm43s

    Epidemiology/Transmission of COVID-19:

    Seroprevalence of COVID-19:

    https://www.youtube.com/watch?v=xIQrzG6bgd4

    How Long Does SARS-CoV-2 Survive in the Body?

    https://www.youtube.com/watch?v=FjbDnDh9aRc

    14 Common Masks Efficacy:

    https://www.youtube.com/watch?v=-0D3q9Xvo1M

    Effectiveness of N95 And Surgical Masks:

    https://www.youtube.com/watch?v=XsJJAciw7jg

    Post-pandemic Expectations:

    https://www.youtube.com/watch?v=RlAwUsH0ifA

    Pre-symptomatic and Asymptomatic Transmission:

    https://www.youtube.com/watch?v=HsCivIt2hGQ

    SARS-CoV-2 and the potential for mutations:

    https://www.youtube.com/watch?v=QdHbDN08OOw&t=6s

    How long does SARS-CoV-2 survive on surfaces?

    https://www.youtube.com/watch?v=WlY5LpNJ78Q&t=34s

    Testing/Diagnosing for COVID-19:

    CSF Leak After Nasal Swabbing:

    https://www.youtube.com/watch?v=8gFRWEXWFlc

    Interpreting Diagnostic Tests for COVID-19:

    https://www.youtube.com/watch?v=dM2pfY2EuYU

    COVID-19 and RT PCR versus CT chest:

    https://www.youtube.com/watch?v=igSSkouQPYo&t=1s

    COVID-19 laboratory work up:

    https://www.youtube.com/watch?v=UM5Jr4aHmQc

    Post-Recovery after COVID-19:

    Persistent symptoms after healing from COVID:

    https://www.youtube.com/watch?v=ieZ6lNwkFqs

    Post-recovery cardiac inflammation after COVID:

    https://www.youtube.com/watch?v=cNFu4phkOmU